DataStatPro topic collection

Sample Size and Study Design Guides

Use these guides before data collection to document the assumptions behind recruitment targets. The collection explains why calculators disagree, how repeated measurements affect power, and how to separate an analyzable target from the number that must be recruited.

Core answer

A defensible sample size follows from the primary hypothesis, statistical model, effect-size definition, alpha, power, allocation, design effects, and expected loss to follow-up.

How to use this collection

Begin with the guide closest to your immediate decision. Record the assumptions, settings, and definitions you use, then open the linked DataStatPro workflow to apply the method. Educational examples should be adapted to the actual study protocol and data structure.